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Meanwhile, the physiological effects of all illegal drugs combined kill an estimated 17,000 Americans annually (Mokdad et al., 2004), a number that is only just above the number of annual deaths (16,500) from nonsteroidal inflammatory drugs (NSAIDs) such as aspirin and ibuprofen (Frech & Go, 2009)

[375] UN Commission on Human Rights, Report of the Special Representative of the Secretary-General, Annex, I.A.1, March 2011, (accessed March 10, 2014)

Tinkering with the chemical composition of cannabis could also make the drug safer without altering the pleasurable effects users want, they add

These are not passive habits